Bernard E Weissman Selected Research

Small Cell Carcinoma

1/2020	Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type.
12/2018	Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type.
1/2018	Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of the Ovary Hypercalcemic Type (SCCOHT) through Multikinase Inhibition.
1/2017	The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.
2/2016	Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.

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Bernard E Weissman Research Topics

Disease

18	Neoplasms (Cancer) 12/2020 - 02/2003
5	Small Cell Carcinoma 01/2020 - 02/2016
4	Carcinogenesis 01/2019 - 03/2003
3	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 01/2018
3	Carcinoma (Carcinomatosis) 12/2011 - 05/2005
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2020 - 02/2003
1	Hyperplasia 10/2020
1	Hypersensitivity (Allergy) 01/2017
1	Rhabdoid Tumor (Rhabdoid Tumors) 02/2015
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2014
1	Neuroblastoma 10/2004
1	Primitive Neuroectodermal Tumors (PNET) 02/2004
1	Infections 03/2003
1	Adenocarcinoma of Lung 02/2003
1	Lung Neoplasms (Lung Cancer) 02/2003

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 12/2020 - 02/2003
7	Adenosine Triphosphatases (ATPase)IBA 12/2020 - 02/2003
3	ChromatinIBA 12/2020 - 02/2015
2	RNA (Ribonucleic Acid)IBA 10/2020 - 01/2019
2	Messenger RNA (mRNA)IBA 01/2019 - 12/2011
2	Histone Deacetylase InhibitorsIBA 12/2018 - 04/2014
2	Phosphotransferases (Kinase)IBA 01/2018 - 02/2015
2	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 03/2005 - 02/2003
1	Keratin-14 (Keratin 14)IBA 10/2020
1	Mutant Proteins (Protein, Mutant)IBA 10/2020
1	PlatinumIBA 01/2020
1	Arginine (L-Arginine)FDA Link 01/2020
1	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 01/2020
1	taxaneIBA 01/2020
1	ADI PEG20IBA 01/2020
1	XenobioticsIBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	Sucrose (Saccharose)IBA 01/2019
1	Kelch-Like ECH-Associated Protein 1IBA 01/2019
1	Histones (Histone)IBA 12/2018
1	quisinostatIBA 12/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	ponatinibIBA 01/2018
1	GSK-2816126IBA 01/2017
1	tazemetostatIBA 01/2017
1	Histone MethyltransferasesIBA 01/2017
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 02/2015
1	AZD 6244IBA 02/2015
1	MitogensIBA 02/2015
1	Mitogen-Activated Protein KinasesIBA 02/2015
1	MicroRNAs (MicroRNA)IBA 02/2015
1	MethyltransferasesIBA 04/2014
1	A-Form DNA (A-DNA)IBA 04/2014
1	Proline (L-Proline)FDA Link 12/2011
1	Glutamine (L-Glutamine)FDA Link 12/2011
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 04/2007
1	Retinoblastoma ProteinIBA 04/2007
1	Decitabine FDA Link 05/2005
1	Cadherins (E-Cadherin)IBA 05/2005
1	CytokinesIBA 03/2005
1	Differentiation AntigensIBA 02/2004
1	Transforming Growth Factor beta (TGF-beta)IBA 03/2003

Therapy/Procedure

2	Therapeutics 01/2020 - 01/2019
1	Drug Therapy (Chemotherapy) 01/2020